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Instead, Omada received feedback from primary care providers, as well as from its employer customers, that the rapidly changing GLP-1 landscape was becoming too complex a burden for the providers to bear on their own

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Other combinations of entero-pancreatic hormones, including cagrisema (GLP-1/amylin RA) and the triple agonist retatrutide (GLP-1/GIP/glucagon RA), have progressed to phase 3 trials as obesity treatments, and early data suggest that they may lead to even greater weight loss than tirzepatide [28]

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